My fundamental belief is that the best registry cleaner is no registry cleaner at all.
also agree-used to use the registry function of ccleaner and pctools registry mechanic and tuneup utilities all on the same computer and would clean the registry with all on a regular basic-"no more" after couple of blue screens and boot up problems and etc-as a saying from bob who always tells me-if it ain't broke-why fix it ::) ;)

What’s the best registry cleaner?-------NONE!!!