I moved the problem software to another drive and that solves the immediate problem.

Opened it fine using AutoSandbox allowing the program to open normally all the time.

I probably had done that previously, and the reason Auto SandBox was asking today is I had to uninstall and reinstall Avast due to an issue with updating my virus definitions.

I will delete the DVD Shrink program files from my F drive and simply use it from my W drive.

Solution works, but problem not really solved.

Thoughts?