Avast 2015 (10.3.2225) kills Office 2013

You could have installed the latest beta as already mentioned. It addressed the Office problem.
https://forum.avast.com/index.php?topic=176033.0

I’ve been experiencing the same issue for Outlook 2013 (Office 365) on Windows 7 x64, but Office 2010 apps working flawlessly. Reverted back to avast! Antivirus 10.2.2215. Looking forward to a fix in next update.

Same problem windows 10 + oficce 2013 64x + avast I told to the cumstumer center and they said it was a problem of my o.s… I think they don`t pretened solve this issue…

there’s no more avast in my p.c. … I have payed for the premiun versión till April 2016.

and i will not recomended it anymore

Have you installed the latest version of Avast ???
https://forum.avast.com/index.php?topic=176600.0

I had the same issue. Office 365 wouldn’t open on 64-bit Windows 7 with Avast installed. I was getting error message 0xc0000005 popping up when I tried to open Word, Excel or Outlook. After weeks of calling Microsoft all kinds of unflattering it names, I found this thread and realised it wasn’t Microsoft’s fault (sorry MS). Thanks to everyone for posting about it. You’ve saved me a ton of headaches.

I’ve uninstalled Avast, and Office 365 is working fine. It’s a shame because I liked Avast, but the ability to do my job is more important to me than Avast is, so it’s gone until they fix it.

I also had a problem upgrading to Windows 10, which may or may not be related. When I tried the free Windows 10 upgrade, it locked me out of all my files by changing the permissions on them. The only fix Microsoft gave me was reverting back to Windows 7 and wasting two weeks of my life–an unplanned/unpaid holiday from work that I wouldn’t recommend–changing the permissions back. Do you think Avast caused that too? I’m wary of trying to install Windows 10 again in case it screws everything up like last time, but if anyone else had the same issue and it was Avast, I’d love to find out.

Hey so I managed to find a fix for this problem for our avast business installs and office 365 - 2016 and 2013 versions

1 - Pause Avast file & Mail shield
2 - Add/remove programs, right click, repair installation - long or short repair it doesn’t matter
3 - Restart shields.

And now everything works again (Avast+Office).

There is no fix at all needed.
In case you missed it, this thread is about avast 2015.
Latest version is 2016 and the problem has been solved.

same problem today
avast free installed in mar 2016
uninstaled today(+uninstal tool), but noting helps >:( >:( >:(