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Office 2016 has been updated by Microsoft recently to version 1702 (in my case earlier this week). Outlook now has a number of problems for those of us using POP3 accounts. The most widely reported is that Outlook searches return no results. The same circumstances seem to affect the Avast add-in, so I think this is a wider problem that MS need to fix. I rolled my Office back to version 1701 (build 16.0.7766.2060); this has restored both Outlook Search and the Avast add-in. Instructions here for anyone who is interested:
https://support.microsoft.com/en-us/help/2770432/how-to-revert-to-an-earlier-version-of-office-2013-or-office-2016-click-to-run