Deleting would cause all kinds of problems. Uninstalling it via add/remove or programs and features would’ve been safer.

There’s also a final uninstall tool available at Comodo forums (use at own risk): http://forums.comodo.com/install-setup-configuration-help-cis/uninstaller-tool-for-comodo-products-t71897.0.html

There’s also this page: https://singularlabs.com/uninstallers/security-software/

or this one: https://www.avast.com/faq.php?article=AVKB11#artTitle