Is there a reason you wish to keep this file? 41/48 detection rate would immediately result in a total and complete toss of whatever the file is just for my safety and sanity alone. Is it a part of a program?

McAfee’s properties description of this threat here: http://home.mcafee.com/virusinfo/virusprofile.aspx?key=2225263

First thing to do: Quarantine the file (you have that option per your screenshot) and then right-click it and upload it to avast! so they can have a look at it. Your file is much safer in quarantine than out in the open; in quarantine it can do no harm to your system.