I tried enlarging the chest size but it still would not process.

After I changed the settings, Avast did allow me to delete the pagefile.sys. Because I was nervous, I chose the option to send it to the Recycle folder instead of a direct permanent deletion.

Since there was still an uninfected pagefile on the C drive and two would have been more than the recommended amount, I just let the F drive remain without one.

(Based on some other things that I read, probably a smarter move would be to have the remaining pagefile.sys on the F drive instead of the C drive, which I may go ahead and change.)

Again, thanks for your time in considering this.