When trying to launch SAFE ZONE from Avast Internet Security, I get a pop-up with the text,
Sorry, the process virtualization feature will be activated upon reboot of the system. Do you want to reboot the system now?
I say yes, and reboot, and when I try to launch, I get the same error pop-up.
I’ve gone into Uninstall and “Repaired” the software, that didn’t do anything
Okay, I fixed it.
I had to reinstall the program AGAIN, this will be my 3rd time uninstalling, and reinstalling.
Make sure to use the Avast Uninstall utility, do a search.
The trial worked great, now that I’ve paid money, I start to have issues, wtf!
Write down your config (at least OS, SP and Avast version)… this might help other forum users! 
Personally, when I was running XP SP3 I encountered randomly BSOD when clicking “Go to SafeZone” from within Firefox (I think was v25 or 26) with avast v9 (if I remember well was .2013)… but it worked perfectly from within IE or from the standard icon on the desktop … no issues on Win7 SP1 at all … (unfortunately, that’s the story of v9 so far: low robustness, thus it is improving with every version :
)