It happens on the first opening of FireFox for me on every system I have updated to the latest version of Avast Free 10.3.2225, so this is definitely something new that Avast is doing which is causing it. My last pc to be updated logged in first time, every time until I did the update and reboot, now it’s the same as my desktops.

Close down FF and restart then it works perfectly from then on until next reboot. So it’s must be something to do with the way the WebShield kicks in when the browser is opened for the first time.

If you turn off all shields and start FireFox for the first time, after a reboot, Lastpass logs straight in first time.