It’s a couple of days that I am tracking down a strange issue between Thunderbird updated to 78.12.0 and Avast Mail Shield (Premium Sec. v21.5.6354.680).
Essentially a cannot connect the POP3 and SMTP servers of my Outlook.com & Gmail.
I verified the accounts’ settings by installing Thunderbird into a Windows Sandbox they working fine.
I set TB ‘security.tls…’ settings, cleanup, and reimport Avast certificate,… but the only thing that worked is to disable both incoming & outcoming mail scan.