avast! Pro Antivirus not initializing

I tried to initialize avast! Pro Antivirus, but the GUI is not showing
I keep double clicking it but still.
What can I do?

have you tried avast repair?

It would be easier if you kept all this in the one original topic http://forum.avast.com/index.php?topic=138814.30 but since you have created yet another thread try rebooting three times with 10 minute intervals between each reboot to let the windows cache repopulate.