since you are running to AV programs at the same time ( avast and MSE ) it is a high risk that this is just False Positive detection

Running two AV can create all kind of mysterious windows errors and false positive detections

Never install two antivirus (see reply from quietman7)
http://www.bleepingcomputer.com/forums/index.php?s=7c8217673a726b92cfc91ecfd4294a29&showtopic=260844&view=findpost&p=1441638

Uninstalling third-party antivirus software (Removing your Current AV)
https://support.avast.com/index.php?languageid=1&group=eng&_m=knowledgebase&_a=viewarticle&kbarticleid=574

Who do I trust? Is Internet Security Essentials just trying to get me to buy their service which is required for them to fix/remove these viruses. Please help, I am not very virus savvy
MSE is free and will remove anything it finds for free.....unless you are infected with a Fake/Rogue MSE program?