Thanks for the reply, I have carried out the following tasks:
I switched off system restore, rebooted in safe mode and ran the virus checker, 8 trojans were found but were not moved to the virus chest as there was an RPC(?) failure.
I have attempted to follow the links regarding host files and instructions relating to these but the virus opens up a search page titled ‘One More Search’ and get several popups titled ‘One Of The Best’.
Are there any other tasks that I can carry out to try and get rid of this virus?