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This brings Microsoft’s brilliant Enhanced Mitigation Experience Toolkit (EMET) to mind. EMET would be the only means by which a user can hobble Avast with the useless baggage of DEP amd ASLR. Avast has self-defence and is presumed trustworthy so I would have thought that DEP/ASLR would at best be a waste of time and at worst would kill Avast and so kill its protection capabilities.
EMET version 5 (production release) is here and it works great.