I just discovered these entries in my Avast self defense log.
6/24/2010 2:45:34 AM Write access to file \Device\HarddiskVolume1\Program Files\Alwil Software\Avast5\AvastUI.exe denied. [C:\WINDOWS\Explorer.EXE]
6/28/2010 11:40:54 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Antivirus\ denied. [C:\WINDOWS\system32\services.exe]
6/28/2010 11:40:56 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Mail Scanner\ denied. [C:\WINDOWS\system32\services.exe]
6/28/2010 11:40:56 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Web Scanner\ denied. [C:\WINDOWS\system32\services.exe]
7/9/2010 5:57:40 PM Write access to registry key \REGISTRY\MACHINE\Software\ALWIL Software\Avast\5.0\ denied. [C:\DOCUME~1\Donald\LOCALS~1\Temp\is-PRJ36.tmp\siw-setup.tmp]
7/9/2010 5:57:47 PM Write access to registry key \REGISTRY\MACHINE\Software\ALWIL Software\Avast\5.0\ denied. [C:\DOCUME~1\Donald\LOCALS~1\Temp\is-PRJ36.tmp\siw-setup.tmp]
7/29/2010 5:27:39 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Antivirus\ denied. [C:\WINDOWS\system32\services.exe]
9/8/2010 6:00:23 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Antivirus\ denied. [C:\WINDOWS\system32\services.exe]
9/8/2010 6:00:24 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Mail Scanner\ denied. [C:\WINDOWS\system32\services.exe]
9/8/2010 6:00:24 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Web Scanner\ denied. [C:\WINDOWS\system32\services.exe]
9/15/2010 3:16:51 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Antivirus\ denied. [C:\WINDOWS\system32\services.exe]
9/15/2010 3:16:51 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Mail Scanner\ denied. [C:\WINDOWS\system32\services.exe]
9/15/2010 3:16:51 PM Write access to registry key \REGISTRY\MACHINE\System\CurrentControlSet\Services\avast! Web Scanner\ denied. [C:\WINDOWS\system32\services.exe]
What could be going on and is it anything to worry about?