Eddy
2
The instructions say to go to the Mail Protection Wizard
It also says :
If you use avast! 4.5 or newer and your operating system is Windows NT, 2000, XP or 2003, you don't have to do any special settings, even for other email clients. avast! 4.5 features a new method of email protection that is very easy for the user - it works completely automatically.
Besides IE is not a mail client. What are you using to check the mail?