I have the same problem!!
Avast free edition sees the FTPUtilsU.dll in Serif software as a Trojan 
I use Serif DrawPlus X5 and Serif WebPlus X6 almost everyday, but after installing the latest Avast updates today I can’t run the programs, because Avast now detects my software as Trojans >:(
…when I make the exclusions in Avast, like you Guys suggest, I’ll get a chance to reinstall my software when I run the DrawPlus.exe and WebPlus.exe, but then again Avast will start blogging the software from installing!!
It’s very confusing and annoying…