All softwares are made by humans,it can only be improved on not made perfect.Even mighty uncle google can fetch you searches for this:
http://lmgtfy.com/?q=how+much+malware+comes+out+everyday%3F
http://lmgtfy.com/?q=No+antivirus+is+100%25
http://lmgtfy.com/?q=sandboxing+and+HIPS+vulnerabilities