Six HIPS programs reviewed and rated here: http://www.techsupportalert.com/security_HIPS.htm
Traditional antivirus solutions cannot protect you until after they’ve discovered a new threat and produced a signature to counter it.
HIPS tools are different because they don’t rely on signatures, but instead constantly analyze your computer’s behavior to detect and block any malicious activity.
HIPS products on the market… (freeware and shareware):
AbuseShield
Abtrusion Protector
All-Seeing Eye
Anti exe
AntiHook
AppDefend
Blink
Coreforce
Cyberhawk
DefenseWall
DSA
Geek SuperHero
NeovaGuard
Online Armor
Ossurance Desktop
Prevx1
ProcessGuard
Prosecurity
RegRun
SafePC
Safe’n’Sec
SoftClan Integrity
SecuriTask
System Safety Monitor (SSM)
Trust-No-Exe
ViGuard
WinPatrol
Winpooch