system
1
Does it make any sense to use both?
igor0
2
Depends on what “use” really means.
Usually, you shouldn’t need to use the avast! Virus Cleaner at all. Besides, if avast! resident protection detects a virus supported by the avast! Virus Cleaner, it offers you to start it.
What exactly do you want to do? 
system
3
well… I’ve had this trojano-247 (or still have…?)
I’ve run scans that found nothing with Home edition, but then found something when running a scan including the archives, plus some other files it said it could not scan…
I then found out about the Virus Cleaner, so I thought why not run a scan with that too…
But I got your point…
system
4
The stand-alone virusCleaner features a list with supported viruses/trojans/worms, and imho Trojan-247 is not on it…

→ http://www.avast.com/eng/avast_cleaner.html
In fact the stand-alone Cleaner only “CLEANS” worms and 1 “true” classic Virus
igor0
5
There’s a list of malware supported by avast! Virus Cleaner on the corresponding web page - there’s no use to try it on other viruses (such as Trojano-something), it won’t work.
system
6
:-[ah…uh…ok…
But can consider I’ve gotten rid of that trojan if several scans of Home edition don’t find it anymore?
Also, is it important to re-activate system restore, what if I leave it disabled?
igor0
7
I think you can say it’s gone. Of course, I suppose you have a fully updated operating system; if not and the virus explots some kind of OS vulnerability, it may come back later.
It’s up to you to re-activate the system restore… some people find this feature useful, the others useless. Decide 
After I had a virus I left system restore disabled as for some reason it had 42000 files in it, used to take ages to do scan, I certainly would not use it again 