How do I know if a Decompression Bomb is safe???

I’ve just received a warning stating “Error:The file is a decompression Bomb (42110)”. It was part of a game download. Is it safe to ignore??
The file is an iso file.

http://forum.avast.com/index.php?topic=84249.0
http://forum.avast.com/index.php?topic=8943.msg73950#msg73950
http://forum.avast.com/index.php?topic=15389.msg131213#msg131213

and you find more if you use forum search

Cheers… I wasn’t sure if the numbers were all different therefore making the bomb different…