Adobe came up with two emergency fixes, see: http://helpx.adobe.com/security/products/flash-player/apsb14-13.html
but users are still asked to refrain from using Blue E for the time being:
http://www.us-cert.gov/ncas/current-activity/2014/04/28/Microsoft-Internet-Explorer-Use-After-Free-Vulnerability-Being
If you cannot do without using IE version 6 up to and including 11, then use additional EMET 4.1 to be more secure.
At the moment there are safeR alternatives like Opera, Firefox, Safari, Chrome.
For Chrome Adobe Flash Player is automatically being patched internally.
pol