Information requested:

Avast - 17.3.2291 ( build 17.3…3443.0) Virus defs: 170411-2
Comodo - 10.0.1.6209
OS 32 Bit Windows XP - Version 5.1 ( Build 2600.xpsp_sp3_qfe.130704-21: Service Pack 3)

I also have Spybot -2.4.40.0, although my issues with Comodo and Avast interacting occurred even when this was uninstalled completely.