thank you for your help so far, before i fix those things, i have a few questions.

why are these 2 harmful, they belong to trend micro and bit defender virus scans, they were active x, which they said i had to install before i could run the scans?

o16 - dpf: {74d05d43-3236-11d4-bdcd-00c04f9a3b61} (housecall control) - http://a840.g.akamai.net/7/840/537/2004061001/housecall.tren dmicro.com/housecall/xscan53.cab
o16 - dpf: {80dd2229-b8e4-4c77-b72f-f22972d723ea} (avxscanonline control) - http://www.bitdefender.com/scan/msie/bitdefender.cab

you said to fix:

o4 - hklm..\run: [messengerplus2] “c:\program files\messenger plus! 2\msgplus.exe”
o4 - hkcu..\run: [msnmsgr] “c:\program files\msn messenger\msnmsgr.exe” /background

these seem to belong to the msn messenger programme, do they still need to be fixed?

what about these 3 entries, are they harmful:should they be fixed

O9 - Extra button: Messenger (HKLM)
O4 - HKLM..\Run: [msnappau] “C:\Program Files\MSN Apps\Updater\01.02.3000.1001\en-gb\msnappau.exe”
O4 - Global Startup: hp psc 1000 series.lnk = ?

finally i ran the hijack analyzer, it says:

C:\WINDOWS\system32\slserv.exe (nasty) running process. (slserv.exe)
slserv.exe

If you have SiS Drivers installed, this entry is normal. It could also mean that you have been infected by the W32/Gaobot.CR virus. Use an Antivirus to check this.

what do i do about this