Nope, you are using two AV. You need to uninstall one of them:

AV: avast! Antivirus *Disabled/Updated* {2B2D1395-420B-D5C9-657E-930FE358FC3C} AV: Microsoft Security Essentials *Disabled/Updated* {3F839487-C7A2-C958-E30C-E2825BA31FB5} SP: avast! Antivirus *Disabled/Updated* {904CF271-6431-DA47-5FCE-A87D98DFB681} SP: Microsoft Security Essentials *Disabled/Updated* {84E27563-E198-C6D6-D9BC-D9F020245508} SP: Windows Defender *Disabled/Updated* {D68DDC3A-831F-4fae-9E44-DA132C1ACF46}

Go here: http://singularlabs.com/uninstallers/security-software/

If you decide to remove Microsoft Security Essentials, download and run it’s tool. If you decide to remove avast! Antivirus, download avast uninstall tool.
Thouse tools will remove related leftovers.

Windows Defender on Vista /7 is AntiMalware program. It’s fine.

  • Then re-run Combofix and attach here fresh CF log. Then tell me how is your computer running now?