Without knowing (a lot) more details there is nothing we can’t (try to) help you.

At my job the mouse suddenly stopped working.
And... What type of mouse ? What type of connection ? Any error on the screen ? Any error in device manager ? What happens at a (re-)boot ? etc.
So I plugged my wireless mouse at the ubs port of that pc. It has just work for a moment and then it stopped working too!
And... Did you install the drivers for that mouse ? What happens after a (re-)boot ?

What OS/SP ?
Any other problems ?

I search at Google.com for what could be happening and I'm afraid introduced a virus at my pc.
The search results also will show.. - User error - Bad batteries - Broken hardware - Dying hardware - Gremlins - Extraterrestrial life forms - Bad connection(s) - Practical joke(s) etc.