My PCs are detecting Win32:Agent-DEP [Drp] in C:\WINDOWS\Installer\2b6a6.msi\Binary.New_Binary6
The actual msi filename varies but when I hover over it is says it is the MS Picture it 2002 installer dated 7/12/2001 19:29. It’s been on my PCs for years so I wonder whether it is a false positive. If necessary I can let you have a copy of the file (4Mb) if you let me know where to upload.
Just for sure you may want to upload the file to VirusTotal to see if only avast! is detecting the file as virus. In case the file is really a false positive, you can sent the file in password protected archive (write the password in the mail body) to virus@avast.com and as a mail subject write “False Positive”
If it is indeed a false positive, add it to the exclusions lists (Standard Shield, Customize, Advanced and Program Settings, Exclusions) and periodically check it (scan it in the chest), there should still be a copy in the chest even though you restored it to the original location. When it is no longer detected then you can also remove it from the Standard Shield and Program Settings, exclusions.
Also see (Mini Sticky) False Positives, how to report and what to do to exclude them until the problem is corrected.