1. I don’t know anthing about Spyboy.
  2. Without more information on your “got something with registry value”, I couldn’t hazard a guess.

I believe Caution should always be exercised when working with the registry (manually or otherwise) and as others more knowledgable than me recommend that you backup registry before messing with it.

However registry checking/editing tools tend to be better than a manual change as they have a restore function (provided of course, you can get back in to restore) and for the most part will have undergone much testing to ensure they don’t do harm.

Not all registry tools are created equal (poor checks or lousy interface) so do your research.