I assume that after these detections avast also suggested that you do a boot-time scan ?

If so did you schedule a boot-time scan ?

This one:
C:\Qoobox\Quarantine\C\WINDOWS\system32\Drivers\i8042prt.sys.vir_ is infected by Win32:Alureon-FZ

You have had a previous infection and have used combofix as this is the combofix quarantine area, once you have done with combofix, it isn’t something to keep installed as it is constantly updated, so should have been removed along with its quarantined folder/files.

Alureon is a rootkit and if not fully removed could still be hiding some other malware, possibly a trojan downloader and the constant recurrence of these is an indication that there is a hidden or undetected piece of malware (probably a downloader) left on your system.

File C:\Documents and Settings\David Miron\Local Settings\Temp\loader.exe is infected by Win32:Cycler-F [Trj], Deleted
File C:\Documents and Settings\David Miron\Local Settings\Temp\smss.exe is infected by Win32:Cycler-F [Trj], Deleted

So the first thing that I would suggest that you schedule a boot-time scan, avastUI, Scan Computer, Boot-time scan. Don’t go deleting thins as your first option (you have none left), select Send to Chest.