rootkit help

I am helping an 81 year old Grandmother with an apparent rootkit.

I’ve tried mbr.exe which said it worked but didn’t, I tried gemr.exe but it crashed. I just loaded avast and I’m running a scan now.
Any advice or do I just need to format and reinstall?

To complicate things, she lives about 10 hours from where I live, so I can’t get my hands on the pc.

also I have a recent backup on a USB drive. I want the pictures and documents, is there a possibility of being infected from the USB DRIVE?