scan threat

Unable to post with attachment. Get timed out. Did upload instead. URL is http://www.mediafire.com/?bth4nlnxu49bf2i. Machine getting slower and slower. Ran Dr Web in safe mode with networking. It found no infections. I did not as yet run the combofix - should I if no infections were found and should I run in safe mode? Was unable to communicate with the forum from safe mode with networking. And still very slow to ommunicate. Am now back in normal mode. Also, during the Dr Web scan, Windows showed a threat message indicating that Hosts files had been modified. It asked me if I wanted to return to default for Hosts, and I accepted. Also, it appears as if something is preventing me or causing me to get hung up when trying to access certain websites (hotmial, yahoo, etc); I also wonder if something is trying to redirect me. The URL when I access hotmail is http://sn130w.snt130.mail.live.com/default.aspx?wa=wsignin1.0
Not sure whether that means anything, but can only access hotmail when this URL is showing. Cannot access hotmail via MSN web for example.

Please advise. Thanks.

Please advise. Thanks.
Have you tried checking for malware with Malwarebytes ?

Malwarebytes Anti-Malware 1.46 http://filehippo.com/download_malwarebytes_anti_malware/
after install click update so you have latest database before scan
click the remove selected button to quarantine anything found
you may post the scan log here

Pondus, I messed up by posting a new message when really it is still part of the ongoing scan threat saga you were involved in some time ago. Apologies. But yes, we did run that program earlier in the sequence. Thank you though. Andre’