There is no setting in avast to wake the system that I could find. However my PCs are set to turn off the monitor after 20 minutes but turn off the hard drive is set to never. I also have hibernate set to never. I am going to set the timer to do a scan at 11:30 EST which is about 14 minutes from now. The PC will be in use so there will be nothing that needs to be awakened. Let see if that scheduled scan starts, I will let you know the results.