Well, they are not a big deal as long as your Windows is up to date. Microsoft patched the DSO Exploit over 2 years ago. But if you still want to get rid of the Spybot’s DSO Exploit “false positive” you can update your Spybot S&D 1.3 to 1.3.1 Beta.
To get it, run Spybot S&D. In Settings->Settings, tick “Display available beta versions” under “Web update” and then search updates. However, I suggest not to install beta definitions, because it’s possible that you’ll get other false positives after that.