After my update today (database version 0403-6), Avast reported a trojan W32:Trojan.gen{Other} on file C:\mirc\mirc.exe.
This file has been on my computer for over two years, and no virus scanner (avast, online scanners, symantec, AVG) has ever had a problem with it.
When the warning was first posted, I tried the repair option, but then thought better of it - adding the offending file to the Exceptions list, and restoring the original file from my backups (yes, I actually do use backups!)
Could someone confirm whether the latest release could have caused this. I have the zipped or original versions of the mirc.exe file if anyone needs to examine them.