The reported file is part of windows defender and is a hidden file hence the Avast warning. But, you can safely ignore it

Warning This fix is only relevant for this system and no other, using on another computer may cause problems

Be advised that when the fix commences it will shut down all running processes and you may lose the desktop and icons, they will return on reboot

Run OTL

[*]Under the Custom Scans/Fixes box at the bottom, paste in the following

https://dl.dropbox.com/u/73555776/OTL_Fix.GIF


:Commands
[CREATERESTOREPOINT]

:OTL
IE - HKLM\SOFTWARE\Microsoft\Internet Explorer\Main,Start Page = http://websearch.searchiseasy.info/?pid=499&r=2013/08/26&hid=12071195910811923614&lg=EN&cc=NL&unqvl=33
IE - HKLM\..\SearchScopes,DefaultScope = {9BB47C17-9C68-4BB3-B188-DD9AF0FD2406}
IE - HKLM\..\SearchScopes\{274daec0-c4e8-4f30-9e5c-9424990769b9}: "URL" = http://search.tb.ask.com/search/GGmain.jhtml?p2=^0D^xdm269^YYA^nl&ptb=8496634C-3569-4DA1-9035-0A4D14805F57&ind=2013101914&n=77fd7f5a&psa=&st=sb&searchfor={searchTerms}
IE - HKLM\..\SearchScopes\{84dc9f6c-c9a5-4c64-ab67-d6ef60f963c8}: "URL" = http://search.mywebsearch.com/mywebsearch/GGmain.jhtml?p2=^ZO^xdm043^YY^nl&si=EL_UTFIG_20&ptb=88A375E7-7249-4CFA-8113-3D9BD2437756&ind=2013040311&n=77fc8eb7&psa=&st=sb&searchfor={searchTerms}
IE - HKLM\..\SearchScopes\{9BB47C17-9C68-4BB3-B188-DD9AF0FD2406}: "URL" = http://dts.search-results.com/sr?src=ieb&gct=ds&appid=295&systemid=406&apn_dtid=BND406&apn_ptnrs=AG6&o=APN10645&apn_uid=3533238505504138&q={searchTerms}
IE - HKLM\..\SearchScopes\{9BB47C17-9C68-4BB3-B188-DD9AF0FD2A59}: "URL" = http://search.imesh.com/web?src=ieb&systemid=1&q={searchTerms}
IE - HKLM\..\SearchScopes\{a5b9c0f5-5616-47cd-a95f-e43b488faccf}: "URL" = http://search.mywebsearch.com/mywebsearch/GGmain.jhtml?p2=^XP^man000^^&ptb=FC8630D7-B29E-4916-86DC-C6D871871645&psa=&ind=2013012009&st=sb&n=77fc2029&searchfor={searchTerms}
IE - HKLM\..\SearchScopes\{afdbddaa-5d3f-42ee-b79c-185a7020515b}: "URL" = http://search.conduit.com/ResultsExt.aspx?q={searchTerms}&SearchSource=4&ctid=CT2857573
IE - HKLM\..\SearchScopes\{BB74DE59-BC4C-4172-9AC4-73315F71CFFE}: "URL" = http://websearch.searchiseasy.info/?l=1&q={searchTerms}&pid=499&r=2013/08/26&hid=12071195910811923614&lg=EN&cc=NL&unqvl=33
IE - HKLM\..\SearchScopes\{cf6e4b1c-dbde-457e-9cef-ab8ecac8a5e8}: "URL" = http://search.tb.ask.com/search/GGmain.jhtml?p2=^HJ^xdm255^YYA^nl&si=COnWlNmwp7kCFYRP3godQCsABQ&ptb=29232A43-4DA6-4832-AED8-0D87C8C61ABA&ind=2013083105&n=77fd35e1&psa=&st=sb&searchfor={searchTerms}
IE - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\URLSearchHook: {213c8ed6-1d78-4d8f-8729-25006aa86a76} - No CLSID value found
IE - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\URLSearchHook: {327f75ed-061b-4339-8cc6-5dd45ad1396d} - No CLSID value found
IE - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\URLSearchHook: {5bcf818d-78c8-41b8-ba89-65c5fdac4fc4} - No CLSID value found
IE - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\URLSearchHook: {b2bf7b3f-bf0b-4c48-aec6-f92c51be63e1} - No CLSID value found
IE - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\SearchScopes,DefaultScope = {6A1806CD-94D4-4689-BA73-E35EA1EA9990}
IE - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\SearchScopes\{274daec0-c4e8-4f30-9e5c-9424990769b9}: "URL" = http://search.tb.ask.com/search/GGmain.jhtml?p2=^0D^xdm269^YYA^nl&ptb=8496634C-3569-4DA1-9035-0A4D14805F57&ind=2013101511&n=77fd7dc7&psa=&st=sb&searchfor={searchTerms}
FF - HKEY_CURRENT_USER\software\mozilla\Firefox\Extensions\\specialsavings@vshsolutions.com: C:\Users\AVVE Solutions\AppData\Roaming\Mozilla\Extensions\specialsavings@vshsolutions.com [2013-01-20 15:53:02 | 000,000,000 | ---D | M]
[2013-01-20 15:53:02 | 000,000,000 | ---D | M] (Special Savings) -- C:\Users\AVVE Solutions\AppData\Roaming\Mozilla\Extensions\specialsavings@vshsolutions.com
O2 - BHO: (Toolbar BHO) - {074d3229-0a22-491b-b9dd-ff3171d75f25} - C:\Program Files\MarineAquarium3Free_57\bar\1.bin\57bar.dll (MindSpark)
O2 - BHO: (Search Assistant BHO) - {0eeaa2c3-0cd7-4364-b82e-f9257081c860} - C:\Program Files\MarineAquarium3Free_57\bar\1.bin\57SrcAs.dll (MindSpark)
O2 - BHO: (MediaBar) - {28387537-e3f9-4ed7-860c-11e69af4a8a0} - C:\Program Files\iMesh Applications\MediaBar\ToolBar\imeshdtxmltbpi.dll ()
O2 - BHO: (UrlHelper Class) - {474597C5-AB09-49d6-A4D5-2E8D7341384E} - C:\Program Files\iMesh Applications\MediaBar\Datamngr\IEBHO.dll (iMesh, Inc)
O3 - HKLM\..\Toolbar: (Marine Aquarium Lite) - {07189b84-b33b-4a1e-9b32-ad203c983c20} - C:\Program Files\MarineAquarium3Free_57\bar\1.bin\57bar.dll (MindSpark)
O3 - HKLM\..\Toolbar: (MediaBar) - {28387537-e3f9-4ed7-860c-11e69af4a8a0} - C:\Program Files\iMesh Applications\MediaBar\ToolBar\imeshdtxmltbpi.dll ()
O3 - HKLM\..\Toolbar: (no name) - 10 - No CLSID value found.
O3 - HKU\S-1-5-21-459960741-3575779535-305645799-1008\..\Toolbar\WebBrowser: (Marine Aquarium Lite) - {07189B84-B33B-4A1E-9B32-AD203C983C20} - C:\Program Files\MarineAquarium3Free_57\bar\1.bin\57bar.dll (MindSpark)
O4 - HKLM..\Run: [Marine Aquarium Lite Search Scope Monitor] C:\Program Files\MarineAquarium3Free_57\bar\1.bin\57SrchMn.exe (MindSpark)
O4 - HKLM..\Run: [MarineAquarium3Free_57 Browser Plugin Loader] C:\Program Files\MarineAquarium3Free_57\bar\1.bin\57brmon.exe (VER_COMPANY_NAME)
[2013-09-29 09:58:21 | 000,000,000 | ---D | C] -- C:\Program Files\WinZip Registry Optimizer

:Files
C:\Program Files\iMesh Applications
C:\Program Files\MarineAquarium3Free_57\bar

:Commands
[resethosts]
[emptytemp]
[Reboot]

[*]Then click the Run Fix button at the top
[*]Let the program run unhindered, reboot the PC when it is done
[*]Open OTL again and click the Quick Scan button. Post the log it produces in your next reply.