i suppose you mean that, when you try to defragment files on your harddrive, it is reported that some files could not be defragmented?
with the avast program installed, when i defragment files on my harddrive, the defragmenter reports that some files could not be defragmented…
if that is the “problem”, i don’t think that it is anything to worry about…
on another note, i think it is a good idea to disable an av-program’s realtime-protection when defragmenting files…