TrojanDownloader:JS/Jesdow.B!url

I have the free version of Avast and it did not find the subject Trojan. I ran it twice and all came up clean. I also ran Malwarebytes AdwCleaner and it did not find this either.

Windows Defender quick scan did not find it but the Advanced scan did.

I am wondering why Avast didn’t find it because that is my primary Antivirus Program? The program is automatically updated.

I am wondering why Avast didn't find it because that is my primary Antivirus Program? The program is automatically updated.
No security program have 100% detection or zero false positives

Did you consider that Windows Defender may be the one that is wrong?

anyway, you give no info
-what files was detected
-at what location … full file path (from detection name it may be a mail attachment ?)
-have you tested detected file at www.virustotal.com … post link to scan result

I also ran Malwarebytes AdwCleaner and it did not find this either.
This is made to clear browser crap

You are not alone: March 31, 2018 > 7 pages
https://answers.microsoft.com/en-us/protect/forum/protect_scanner-protect_scanning-windows_10/trojandownloaderjsjesdowburl/7f1240f2-9db4-488b-a37d-583c7ef94df9

seems to be a WinDefender False Positive in a cyberlink/powerDVD file
https://filestore.community.support.microsoft.com/api/images/6f9a038a-013d-4ee5-8f1c-2c523fc26805?upload=true