An outdated version of Adobe Reader is an security risk.

Uninstall version 10 and install version 11.

Also there are many exploits for Internet Explorer right, so it would be good to use Firefox, Chrome, Safari for Windows, Opera etc.

Symantec just detected some Vulnerabilities:

http://www.symantec.com/security_response/vulnerability.jsp?bid=62811
http://www.symantec.com/security_response/vulnerability.jsp?bid=62819
http://www.symantec.com/security_response/vulnerability.jsp?bid=62453

Also keep Windows Updates up to date, and be careful when installing Software, they install adware often.
And also you can uninstall Java, or if you want to keep it hold it up to date. Newest is Java 7 update 40