Send a file to Chest (Quarantine) is always safer than to delete it immediately.
Into Chest you can scan the file again (and see if it is a false positive or not), you can restore the file (if it’s not infected), you can delete (get rid from it), etc.
Chest is safe to keep a file into.
Of course, if avast suggest the ‘repair’ option, try it first. avast can repair some infections on executable files.
