VPN blocks sending emails

Avast SecureLine VPN
1

VPN being activated, no mail can be sent in Outlook. I receive the error code 0x800CCC, service refused, try later.
After deactivating VPN, the mails are released.

2

Hi, see: https://support.avast.com/en-ww/article/Troubleshoot-SecureLine-VPN-email/