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Adfender is an ad blocker and does not conflict with avast.
Most of us use AdBlock Plus for this purpose.
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Not knowing what the pop-up said it is difficult to know.
Did you click on the “more details” button in the pop-up?
URL:Mal usually means a malicious URL. Generally avast blocks these infections.
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Did you run a “full system scan” before you did the reformat?
If you did what was found or was anything at all found?
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Pondus knows what he’s talking about. Avast with MalwareBytes and MCShield make good partners.
For a one time charge of $25 gets you a lifetime license to MBAM Pro. Purchase it before MBAM
releases v2.0 or else it will be an annual charge.