Many big-name anti-virus products failed to secure Windows 2000 in recent independent tests.
http://www.theregister.co.uk/2007/12/04/win_2000_virus_tests/
There is a topic on this at http://forum.avast.com/index.php?topic=31836.msg265769#msg265769, avast had 1 false positive.
OK, thanks, missed that.