I guess I'll reinstall Avast and keep TDSSkiller handy!
well it is not a program you keep like that...as it needs updates and since it does not have a update button to click you need to download latest updated version from Kaspersky web when you need it ;)

You say Malwarebytes will not run…that often indicate infection as many bugs will try blocking it from running

so i would post an OTS log and let Essexboy have a look at it