Yes, it makes a lot of sense. If the file you deleted was a downloader that avast! doesn’t yet recognize, it was able to exist on your computer trying to download malware that avast! did recognize. Now that its gone the attempted downloads have ended.

At this point, since avast! didn’t detect everything that was going on, I would run CleanUp followed by a Trend micro on-line scan just to make sure your computer is clean

http://housecall.trendmicro.com/

And if you have only the Windows Firewall on your computer you can consider a third party product which can help prevent this type of problem.

Other than that, have good dreams …