C:\Users\Clare\Downloads\Setup

I ran Avast this morning and got a notepad notification (see below) - I moved it to the virus chest - do I need to do anything else? My PC still seems sluggish - any help?? thanks
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  • avast! Scan Report
  • This file is generated automatically
  • Scan name: Full system scan
  • Started on: Saturday, April 06, 2013 9:01:41 AM
  • VPS: 130405-1, 05/04/2013

C:\Users\Clare\Downloads\Setup (2).exe [L] Win32:IBryte-BE [PUP] (0)
Infected files: 1
Total files: 357231
Total folders: 28934
Total size: 114.8 GB

  • Scan stopped: 06 April 2013 10:23:42

  • Run-time was 1 hour(s), 22 minute(s), 1 second(s)

  • avast! Scan Report

  • This file is generated automatically

  • Scan name: Full system scan

  • Started on: Saturday, April 06, 2013 11:12:11 AM

  • VPS: 130405-1, 05/04/2013

Win32:IBryte-BE [[b]PUP[/b]]
PUP = not a virus/ Possible Unwanted Program
My PC still seems sluggish - any help?? thanks
if you want a check [b]attach[/b] the requested logs from here http://forum.avast.com/index.php?topic=53253.0

AdwCleaner
Malwarebytes
OTL
aswMBR

when done a removal expert will check the logs for any infections