If it did use more ram it would be so little you wouldn’t even notice it but the auto sandbox cannot be removed but you can choose to not use it by unticking the box and site blocking should already be unticked by default.
Im not sure if any other features rely on auto sandbox.
AutoSandbox is basically an integral part of the FileSystem Shield, so it cannot be removed.
But you can disable it if you feel you don’t need it, no other features depend on that.