HELP Error: Access is denied (5)

I recently just performed a full system scan on my computer and found a threat: sansa-installer.exe
I have tried performing all actions in hopes to remove the virus but nothing works. All I get is a notification telling me "Error: Access is denied (5)
If anyone can help, it would be greatly appreciated. Here is an image of the result:

http://i.imgur.com/51PxhuL.png

What is I drive? Is it read only (a CD/DVD maybe)?

For more detailed help:

Please follow the directions for scans in this topic and attach as many of the logs as you can run.
Logs to assist in cleaning malware