Before running any other programs that would delete/quarantine the files.
Send the sample to virus@avast.com zipped and password protected with the password in email body, a link to this topic might help and undetected malware in the subject.
Or you can also add the file to the User Files (File, Add) section of the avast chest (if it isn’t already there) where it can do no harm and send it from there (select the file, right click, email to Alwil Software). No need to zip and PW protect when the sample is sent from chest. A copy of the file/s will remain in the original location, so any further action you take can remove that. Send it from the User Files section of the chest (select the file, right click, email to Alwil Software). This process has been modified in the latest version to make it easier, it doesn’t actually get emailed, but transferred when the next avast auto (or manual) update is done.