The aswMBR locked files are part of Kaspersky so they will need removing, Spybot quarantine holds a lot of bad stuff that will need to be removed
Basically you have gone for overkill
Warning This fix is only relevant for this system and no other, using on another computer may cause problems
Be advised that when the fix commences it will shut down all running processes and you may lose the desktop and icons, they will return on reboot
Run OTL
[*]Under the Custom Scans/Fixes box at the bottom, paste in the following
https://dl.dropbox.com/u/73555776/OTL_Fix.GIF
:OTL
SRV - File not found [Auto | Running] -- C:\Program Files\Spybot -- (SBSDWSCService)
SRV - [2012/11/19 21:27:41 | 000,711,112 | ---- | M] () [Auto | Running] -- C:\Program Files\Common Files\AVG Secure Search\vToolbarUpdater\13.2.0\ToolbarUpdater.exe -- (vToolbarUpdater13.2.0)
SRV - [2012/08/17 20:43:06 | 000,218,880 | ---- | M] (Kaspersky Lab ZAO) [Auto | Running] -- C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\avp.exe -- (AVP)
SRV - [2012/07/12 17:32:22 | 001,239,952 | ---- | M] (Lavasoft Limited) [Auto | Running] -- C:\Program Files\Ad-Aware Antivirus\AdAwareService.exe -- (Ad-Aware Service)
SRV - [2011/12/19 12:20:06 | 003,289,032 | ---- | M] (GFI Software) [Auto | Running] -- C:\Program Files\Ad-Aware Antivirus\SBAMSvc.exe -- (SBAMSvc)
DRV - [2012/11/19 21:27:43 | 000,026,984 | ---- | M] (AVG Technologies) [Kernel | System | Running] -- C:\Windows\System32\drivers\avgtpx86.sys -- (avgtp)
DRV - [2012/08/13 17:24:12 | 000,587,096 | ---- | M] (Kaspersky Lab) [File_System | System | Running] -- C:\Windows\System32\drivers\klif.sys -- (KLIF)
DRV - [2012/08/13 15:49:44 | 000,144,344 | ---- | M] (Kaspersky Lab) [Kernel | System | Running] -- C:\Windows\System32\drivers\kneps.sys -- (kneps)
DRV - [2012/08/02 14:09:30 | 000,024,408 | ---- | M] (Kaspersky Lab ZAO) [Kernel | System | Running] -- C:\Windows\System32\drivers\klim6.sys -- (KLIM6)
DRV - [2012/07/25 13:53:48 | 000,025,944 | ---- | M] (Kaspersky Lab) [Kernel | On_Demand | Running] -- C:\Windows\System32\drivers\klmouflt.sys -- (klmouflt)
DRV - [2012/06/19 16:28:12 | 000,136,024 | ---- | M] (Kaspersky Lab ZAO) [Kernel | Boot | Running] -- C:\Windows\System32\drivers\kl1.sys -- (kl1)
DRV - [2012/06/08 10:38:12 | 000,043,608 | ---- | M] (Kaspersky Lab) [Kernel | System | Running] -- C:\Windows\System32\drivers\kltdi.sys -- (kltdi)
DRV - [2012/05/25 18:38:48 | 000,025,432 | ---- | M] (Kaspersky Lab) [Kernel | On_Demand | Running] -- C:\Windows\System32\drivers\klkbdflt.sys -- (klkbdflt)
DRV - [2011/12/19 11:44:24 | 000,093,816 | ---- | M] (GFI Software) [Kernel | On_Demand | Stopped] -- C:\Windows\System32\drivers\sbhips.sys -- (sbhips)
DRV - [2011/11/29 05:59:52 | 000,077,816 | ---- | M] (GFI Software) [File_System | Auto | Running] -- C:\Windows\System32\drivers\sbapifs.sys -- (sbapifs)
DRV - [2011/10/26 13:23:40 | 000,101,112 | ---- | M] (GFI Software) [Kernel | System | Running] -- C:\Windows\System32\drivers\SBREDrv.sys -- (SBRE)
FF - prefs.js..browser.search.defaultenginename: "AVG Secure Search"
FF - prefs.js..browser.search.selectedEngine: "AVG Secure Search"
FF - HKEY_LOCAL_MACHINE\software\mozilla\Firefox\Extensions\\url_advisor@kaspersky.com: C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\FFExt\url_advisor@kaspersky.com [2012/09/11 03:12:49 | 000,000,000 | ---D | M]
FF - HKEY_LOCAL_MACHINE\software\mozilla\Firefox\Extensions\\virtual_keyboard@kaspersky.com: C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\FFExt\virtual_keyboard@kaspersky.com [2012/09/11 03:12:51 | 000,000,000 | ---D | M]
FF - HKEY_LOCAL_MACHINE\software\mozilla\Firefox\Extensions\\content_blocker@kaspersky.com: C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\FFExt\content_blocker@kaspersky.com [2012/09/11 03:12:04 | 000,000,000 | ---D | M]
FF - HKEY_LOCAL_MACHINE\software\mozilla\Thunderbird\Extensions\\eplgTb@eset.com: C:\Program Files\ESET\ESET NOD32 Antivirus\Mozilla Thunderbird
[2010/03/16 00:02:37 | 000,000,000 | ---D | M] (Zynga Toolbar) -- C:\Users\USER\AppData\Roaming\mozilla\Firefox\Profiles\zpkzyjca.default\extensions\{7b13ec3e-999a-4b70-b9cb-2617b8323822}
[2012/04/22 00:32:52 | 000,000,000 | ---D | M] (DVDVideoSoftTB Toolbar) -- C:\Users\USER\AppData\Roaming\mozilla\Firefox\Profiles\zpkzyjca.default\extensions\{872b5b88-9db5-4310-bdd0-ac189557e5f5}
[2011/12/24 23:28:36 | 000,000,000 | ---D | M] (Kaspersky URL Advisor) -- C:\Program Files\Mozilla Firefox\extensions\linkfilter@kaspersky.ru_bak
O2 - BHO: (no name) - {3CA2F312-6F6E-4B53-A66E-4E65E497C8C0} - No CLSID value found.
O2 - BHO: (Spybot-S&D IE Protection) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll (Safer Networking Limited)
O2 - BHO: (Content Blocker Plugin) - {5564CC73-EFA7-4CBF-918A-5CF7FBBFFF4F} - C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\IEExt\ContentBlocker\ie_content_blocker_plugin.dll (Kaspersky Lab ZAO)
O2 - BHO: (Virtual Keyboard Plugin) - {73455575-E40C-433C-9784-C78DC7761455} - C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\IEExt\VirtualKeyboard\ie_virtual_keyboard_plugin.dll (Kaspersky Lab ZAO)
O2 - BHO: (URL Advisor Plugin) - {E33CF602-D945-461A-83F0-819F76A199F8} - C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\IEExt\UrlAdvisor\klwtbbho.dll (Kaspersky Lab ZAO)
O4 - HKLM..\Run: [Ad-Aware Antivirus] C:\Program Files\Ad-Aware Antivirus\AdAwareLauncher.exe (Lavasoft Limited)
O4 - HKLM..\Run: [Ad-Aware Browsing Protection] C:\ProgramData\Ad-Aware Browsing Protection\adawarebp.exe (Lavasoft)
O4 - HKLM..\Run: [AVP] C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus 2013\avp.exe (Kaspersky Lab ZAO)
O4 - HKLM..\Run: [ROC_roc_ssl_v12] "C:\Program Files\AVG Secure Search\ROC_roc_ssl_v12.exe" / /PROMPT /CMPID=roc_ssl_v12 File not found
O4 - HKLM..\Run: [SBRegRebootCleaner] C:\Program Files\Ad-Aware Antivirus\SBRC.exe (GFI Software)
O4 - HKLM..\Run: [vProt] "C:\Program Files\AVG Secure Search\vprot.exe" File not found
O4 - HKU\S-1-5-21-770305187-3020679099-2410195673-1000..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe (Safer-Networking Ltd.)
[2012/12/27 07:31:42 | 000,001,830 | ---- | M] () -- C:\Users\Public\Desktop\Ad-Aware Antivirus.lnk
:Files
C:\Program Files\Common Files\AVG Secure Search
C:\Program Files\Kaspersky Lab
C:\Program Files\Ad-Aware Antivirus
C:\Program Files\ESET
C:\ProgramData\Ad-Aware Browsing Protection
:Commands
[resethosts]
[emptytemp]
[CREATERESTOREPOINT]
[Reboot]
[*]Then click the Run Fix button at the top
[*]Let the program run unhindered, reboot the PC when it is done
[*]Open OTL again and click the Quick Scan button. Post the log it produces in your next reply.