Smart Scan question.

I ran the avast smart scan in the latest version of avast 2016. Avast is telling me that is not compatible with the latest version of Comodo Internet Security. Do I have anything to worry about or should I ignore it completely? I don’t have any other antivirus besides avast, I only have Comodo Firewall installed.

Here is an image of what the error looks like.

http://i63.tinypic.com/29x6ej7.png

Do I have anything to worry about or should I ignore it completely? I don't have any other antivirus besides avast, I only have Comodo Firewall installed.
since you dont have comodo antivirus installed, Ignore the message .... there will probably be a update/fix from avast

IMHO, it appears that the OP has inadvertently installed the antivirus when they installed CFW.
I would recommend uninstalling CIS completely and do a clean install.

https://www.comodo.com/home/internet-security/firewall.php
Follow these instructions to the letter http://www.techsupportalert.com/content/how-install-comodo-firewall.htm